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Current Research: Gerald H. Jacobs Research in our laboratory is broadly centered on issues having to do with the biology of mammalian vision. To pursue such problems we study a range of animal subjects, from mice to humans, and employ experimental techniques that include psychophysical studies of vision, electrophysiological analysis of visual function, and examination of various structural features of the visual system. A long-term interest is in the study of color vision and its biological basis. For example, some years ago we discovered the presence of significant color vision polymorphisms in some species of nonhuman primate. This discovery led to a series of investigations which eventually revealed the photopigment and genetic bases for these color vision variations. This work has in turn directly impacted our understanding of the evolution of primate color vision and it has provided the basis for a much more detailed view of linkages between genes, photopigments, retinal organization, and vision. Research of this general nature continues in the lab, as does now the study of genetically engineered mice whose retinas have been discretely altered and of some animal models of retinal disease.
Faculty Home | Current Research | Selected Publications
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